Built in the middle of the 16th century by the Order of Mercy, the church’s main highlight is its cedar carved main altar. The carved and gilded altarpieces inside of it are sure to catch your eye. One of them is considered to be the Audiencia of Charcas’ oldest altarpiece. Sixteen famous and Bolivia’s only in situ paintings by the esteemed artist Melchor Pérez de Holguín, along with the baroque-style pulpit, are part of the church’s artistic interest. The pulpit as well as the left side altarpiece were done by the indigenous artist Luis Niño.
The central nave is covered with coffered vaults; one of the aisles with two half-orange-shaped vaults and the other one with a Mudejar coffered ceiling as well as two coffered Renaissance ceilings with four-leaved carvings.